Mar 6, 2025
On this episode of the Somewhat Frank Podcast, Frank Gruber (X and IG: @FrankGruber), John Guidos (IG: jgoodtimes83), and Simon Kahan (IG: @simonkahan) discuss the following topics:
We are hosting the Established House in Austin on Friday, March 7th, with a couple of featured conversations, a barista spinning our delightful lattes and teas and lots of opportunities to connect with one another. If you’ll be in Austin, please join us! RSVP at: est.us/house25
AI Is Changing How Silicon Valley Builds Startups - The traditional Silicon Valley model of heavy fundraising and large headcounts is being replaced by AI-driven efficiency, with companies like Anysphere and ElevenLabs reaching $100M revenue with under 50 workers. Also, here is Frank’s take on it: https://www.linkedin.com/feed/update/urn:li:activity:7299885251869196288/
Mice have been genetically engineered to look like mammoths - Colossal Biosciences genetically engineered mice with mammoth-like fur by altering up to five genes, though only one matches the mammoth genome exactly. Here are some more thoughts on the animal/human hybrid topic: https://www.scientificamerican.com/article/japan-approves-first-human-animal-embryo-experiments/
Digg is coming back, thanks to its founder Kevin Rose — and Reddit’s success - Digg is relaunching with Kevin Rose as chair, Alexis Ohanian as an adviser, and Justin Mezzell as CEO, aiming to revive its “homepage of the internet” legacy.
A Private Space Mission Just Successfully Landed on the Moon for the First Time - Firefly Aerospace’s Blue Ghost lunar module became the first private company’s lander to successfully touch down on the moon, landing on March 2, 2025.
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As always, thank you for listening, and feel free to reach out and let us know what you think at: somewhatfrank@est.us